The fixture will be Unai Emery's first competitive match as Gunners manager.
Mauricio Pochettino's will play their opening home game at Wembley against Fulham before facing Manchester United at Old Trafford in the opening month.
Wenger chose to step down at the end of last season after nearly 22 years in charge of the north London club.
The Blues' defence of the Premier League title kicks off with one of the toughest of tests - a trip to Arsenal.
Excited Arsenal fans were brought back down to earth with a bump after seeing the 2018-19 Premier League fixtures on Thursday morning.
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That stance "confirms the latest unwillingness of Malta and, thus, of Europe , to intervene and take care of the emergency ". Interior Minister Matteo Salvini sent out a message explaining why the ship was being told to hold on station.
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England men's cricket team had scored 444/3 in 50 overs in an ODI match, also against Pakistan, at Nottingham on August 30, 2016. India's highest ODI total is 358/2, notched up against Ireland women at Potchefstroom, South Africa in May a year ago .
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Great in concept, and with space for third party announcements between, it's hard to say that Sony managed to pull it off. It was impressive and the flawless demo for a game that is surely at the top of many people's wish lists.
Arsenal will begin proceedings by hosting the reigning champions at the Emirates before travelling to Stamford Bridge the following weekend. Oof.
The reverse fixture could had seen City win the title against their rivals, however a second half resurgence from United saw City lose 3-2 with a Paul Pogba double and Chris Smalling goal overshadowing the first half performance.
Spurs petitioned to play their first four games away from home, similarly to Liverpool last season before the opening of their new main stand. Tottenham make the trip to Tyneside to play Newcastle United, while Chelsea go to Huddersfield and Manchester United host Leicester City.
Manchester United begin their league campaign at home to Leicester City and face a potentially tricky encounter in their third game when Tottenham Hotspur come to Old Trafford.
The Champions League quarterfinal meeting between the two clubs - with both legs won by Liverpool - also intensified the rivalry between the two sides and October's meeting will also be the first time City will travel to Anfield since their team bus was attacked by missile-throwing supporters prior to the Champions League first-leg tie.
How many points will Arsenal collect from their opening two Premier League games?