Paramedics treated five people at the scene and took two to hospital.
Metropolitan Police officers are at the scene along with the British Transport Police, London Fire Brigade and London Ambulance Service.
"We remain at Southgate Tube station in London following a reported minor explosion".
'We are not aware of any serious injury'.
Metropolitan Police said the blast was thought to be caused by a battery short circuit.
"Please avoid the area - we'll provide updates as soon as we can".
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Twitter user Hal wrote: "I was at Southgate Station when this commotion started".
They closed the station and said officers were dealing with a suspicious package.
Haluk Ozkan was about to get on a bus outside the station when he smelt something burning. However, BTP later tweeted: "Enquiries continue but we do not believe this to be terror related at [this] time".
City worker Darren Yarlett, 36, told the Evening Standard that he was attempting to drive home in the area, but found the roads had been tapered off.
Police are now investigating the incident.
Police have evacuated a Tube station during rush hour after an "explosion" left a number of people injured.