She reportedly then handed a note to security and left following a "stand-off" at the perimeter of the palace.
The confrontation came on a recent trip to the U.K.by the elder Markle, which she reportedly made in order to confront Meghan.
But despite being told to get lost, Samantha was captured handing palace guards a letter which many believed is addressed to Meghan.
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There will be a number of charities among the 1,200 invited guests, including the Royal National Orthopaedic Hospital, the U.N. But this royal wedding brings up a "genuine debate" about Britain's royal family, said BBC News' Simon Bates.
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On Sunday, Samantha teased her Twitter followers, writing, "Everybody would love to know what's in that letter".
And according to royal etiquette specialist Myka Meier, Harry and Meghan's cute handholds and loving embraces are what make them approachable to non-royals. However, arrived in a wheelchair an American (she suffers with multiple sclerosis in 2008), did not let the Palace guards.
Their father, Thomas Markle, was also absent when Meghan married Prince Harry at Windsor in May. "She's mindful that she's representing the Queen and the royal family and doesn't want to put a foot wrong".
Some of her comments seem a bit freaky though and it's hard to figure out what exactly is going on especially after she apologised to Meghan during an appearance on The Jeremy Vine Show last week.
Just days after the couple's wedding on May 19, he said: "I think that even before Meghan has learned how to spell Leicester and Torquay she'll be starting a family".