Spain wanted the future of Gibraltar, a territory on the southern tip of Spain that was ceded to Britain in 1713, to be an issue between Spain and Britain rather than Britain and the E.U. The agreement says that Madrid will be given a say on matters concerning Gibraltar when it comes to future trade deals.
The leader of the Democratic Unionist Party, which usually supports the government, is also opposed to the deal, as are the leaders of the main opposition Labour Party and the much smaller Liberal Democrats.
"Spain is the physical and geographical gateway to Europe for Gibraltar", Picardo told the BBC. She added that she understood that some leaders were sad, and some people at home in Britain were, too.
In the days before the summit, some states raised objections regarding the content of the withdrawal agreement, including over the issue of fishing rights in the UK's territorial waters post-Brexit.
"I'll take this deal back to the House of Commons confident we've achieved the best deal available and full of optimism about the future of our country", May said at a news conference in Brussels.
"I'm thinking about getting a deal through that delivers for the people of this country", she added.
The Spanish government, Sánchez said, aims to have "fruitful, close and ambitious" relationship with the territory in the future, that will favour both Gibraltar and the so-called "Field of Gibraltar".
Pro-EU Conservative and former GP Sarah Wollaston said it was "deeply shocking" that the prime minister restated the discredited NHS funding claim.
"Instead we will be able pend taxpayers money on our priorities, like the £394m per week of extra investment into our NHS", she promised.
Samantha Sacramento, the housing minister of Gibraltar - the British territory which has become a last-minute sticking point ahead of the European Union summit - also addressed attendees Saturday.
With all opposition parties and up to 80 Conservative MPs pledged to oppose May's deal when it comes to the House of Commons, Remainer ministers in her Cabinet are pushing for the prime minister to seek an alternative deal that would leave Britain with a closer relationship with the European Union after Brexit.
She said that the draft agreement raises constitutional questions and instead insisted on "an outcome that does not leave Northern Ireland open to the perils of increased divergence away from the rest of the United Kingdom".
UK Prime Minister Theresa May has arrived in Brussels and held talks with top European Union officials, ahead of the summit. The treaty also covers financial matters, citizens' rights and Brexit's impact on Northern Ireland, and sets out hopes for future security and trade ties between the European Union and Britain.
Sanchez said the agreement reached would give Spain "absolute guarantees to resolve the conflict that has lasted for more than 300 years before Spain and the U.K".
His comments came as the Prime Minister travelled to Brussels with her Brexit deal under threat at home and overseas.
That included a plan being hatched by close allies such as finance minister Philip Hammond and work and pensions minister Amber Rudd, reported The Sunday Times without citing sources.
Eurosceptic Tory MP Andrew Bridgen, a prominent critic of the Prime Minister, said: "With regard to the Withdrawal Agreement and the proposed future relationship "never in the history of our great nation have so many been betrayed, so deliberately, for so little".
The small DUP has an outsize role because its support has been crucial to May's shaky government, which doesn't enjoy a majority in Parliament.
During a radio grilling from the public, Mrs May refused to rule out resigning as Prime Minister if her highly contentious Brexit divorce deal is voted down.
European Council president Donald Tusk said on Sunday morning that an agreement had been reached.
Negotiations continued up to the last minute on the 585-page withdrawal agreement, which has drawn fierce criticism from euroskeptics as well as pro-EU politicians in Britain.
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